This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[
Immunogen Information
Immunogen
Recombinant protein of human TAX1BP1
Swissprot
Q86VP1
Synonyms
1200003J11Rik1700069J21RikAa1076AA930106CALCOCO 3CALCOCO3D6Ertd404eD6Ertd772eHuman T cell leukemia virus type 1-binding proteinLiver regeneration-related protein LRRG004MGC94031PRO0105T6BPTax1 (human T cell leukemia virus type I) binding prot
Gene Accession
BC050358
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4