TAZ Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD266586A
Immunofluorescence analysis of U2OS cells using TAZ Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
TAZ Polyclonal Antibody
Catalog Number
RD266586A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
TAZ, also referred as WWTR1, is a transcriptional co-activator with a PDZ-binding motif that is regulated by its interaction with 14-3-3 protein. TAZ is expressed in many primary tumors, such as breast cancer, thyroid carcinoma, colorectal cancer, and glioma. TAZ has been reported to be one of the nuclear effectors of Hippo-related pathways that regulate organ size control, cancer stem cell (CSC) properties, and epithelial–mesenchymal transition (EMT). TAZ has been defined for its role in the nucleus, where it functions directly as a transcriptional regulator by interacting with several nuclear factors as Runx2/Cbfa1, NHERF-2, TEF-1, TBX5, PAX3, PAX8 and TTF-1.
Immunogen Information
Immunogen
A synthetic peptide of human TAZ (NP_056287.1).
Gene ID
25937
Swissprot
Q9GZV5
Synonyms
BTKAGMX1ATATKBPKIMD1PSCTK1XLABruton tyrosine kinaseTAZWWTR1
Applications
Reactivity
Human,Mouse
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas