TBP Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85598A
Western Blot analysis of 1) Hela, 2) Mouse brain, 3) Rat brain using TBP Monoclonal Antibody at dilution of 1:2000.
Product Name
TBP Monoclonal Antibody
Catalog Number
RD85598A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
Immunogen Information
Immunogen
Recombinant Protein
Swissprot
P20226
Synonyms
GTF2DGTF2D1HDL4SCA17TATA binding factorTATA box binding proteinTATA box factorTATA sequence binding proteinTATA sequence-binding proteinTATA-binding factorTATA-box factorTATA-box-binding proteinTBPTBPTFIIDTranscription initiation factor TFI
Observed MW
35-45 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas