TBP Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85600A
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using TBP Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Mouse kidney tissue using TBP Monoclonal Antibody at dilution of 1:200.
Product Name
TBP Monoclonal Antibody
Catalog Number
RD85600A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
Immunogen Information
Immunogen
Recombinant Protein
Swissprot
P20226
Synonyms
GTF2DGTF2D1HDL4SCA17TATA binding factorTATA box binding proteinTATA box factorTATA sequence binding proteinTATA sequence-binding proteinTATA-binding factorTATA-box factorTATA-box-binding proteinTBPTBPTFIIDTranscription initiation factor TFI
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC-p
Conjugation
Unconjugated
Dilution
IHC 1:50-200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas