This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
Immunogen Information
Immunogen
Fusion protein of human TBPL1
Swissprot
P62380
Synonyms
21 kDa TBP-like protein21kDa TBP like proteinSecond TBP of unique DNASecond TBP of unique DNA proteinSTUDTATA box binding protein like protein 1TATA box binding protein-related factor 2TATA box-binding protein-like protein 1TATA box-binding protei