This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development.
Immunogen Information
Immunogen
Synthetic peptide of human TBX3
Swissprot
O15119
Synonyms
Bladder cancer related protein XHLT box 3T-box protein 3T-box transcription factor TBX3Tbx3TBX3 ISOTBX3UMSXHL