This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
Immunogen Information
Immunogen
Synthetic peptide of human TDP2
Swissprot
O95551
Synonyms
5'-Tyr-DNA phosphodiesterase5'-tyrosyl-DNA phosphodiesteraseAD 022AD022dJ30M3.3EAP 2EAP IIEAP2EAPIIETS 1 associated protein 2ETS 1 associated protein IIETS1 associated protein 2ETS1-associated protein 2ETS1-associated protein IIMGC111021MGC