Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Immunogen Information
Immunogen
Recombinant protein of human TFF2
Swissprot
Q03403
Synonyms
SML 1SML1SPSpasmolysinSpasmolytic polypeptidespasmolytic protein 1TFF 2TFF2TFF2trefoil factor 2 (spasmolytic protein 1)Trefoil factor 2Trefoil factor 2 precursor
Gene Accession
BC032820
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4