TGF beta Receptor I (TGFBR1) Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90200A
Western blot analysis of extracts of various cell lines using TGFBR1 Polyclonal Antibody at 1:1000 dilution.
Product Name
TGF beta Receptor I (TGFBR1) Polyclonal Antibody
Catalog Number
RD90200A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
A synthetic peptide of human TGF beta Receptor I
Gene ID
7046
Swissprot
P36897
Synonyms
TGFBR1AAT5ACVRLK4ALK-5ALK5ESS1LDS1LDS1ALDS2AMSSESKR4TGFR-1tbetaR-ITBRITBR-i
Calculated MW
22kDa/29kDa/34kDa
Observed MW
34kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas