The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse TGFβR1
Swissprot
P36897,Q64729,P80204
Synonyms
AAT 5AAT5Activin A receptor type II like kinase 53kDaActivin A receptor type II like kinase53kDActivin A receptor type II like protein kinase of 53kDactivin A receptor type II-like kinase53kDaactivin A receptor type II-like protein kinase of 53kD
Calculated MW
56 kDa
Observed MW
56 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4