TGFBR2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD265842A
Immunohistochemistry of paraffin-embedded Human liver cancer using TGFBR2 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human breast using TGFBR2 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human mammary cancer using TGFBR2 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using TGFBR2 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
TGFBR2 Polyclonal Antibody
Catalog Number
RD265842A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Immunogen Information
Immunogen
Recombinant fusion protein of human TGFBR2 (NP_003233.4).
Gene ID
7048
Swissprot
P37173
Synonyms
AAT3FAA3LDS1BLDS2LDS2BMFS2RIICTAAD2TGFR-2TGFbeta-RIITGF beta Receptor IITGFBR2
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas