Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.
Immunogen Information
Immunogen
Fusion protein of human TGM3
Swissprot
Q08188
Synonyms
E polypeptide protein glutamine gamma glutamyltransferaseMGC126249MGC126250Protein glutamine gamma glutamyltransferase E 27 kDa catalytic chainProtein glutamine gamma glutamyltransferase E 50 kDa noncatalytic chainProtein glutamine gamma glutamyltran