THOC7 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75574A
Western Blot analysis of Mouse spleen and Human fetal liver tissue, hela cell and Mouse testis tissue, A431 cell using THOC7 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human lung cancer using THOC7 Polyclonal Antibody at dilution of 1:30
Variation
Quantity
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Overview
Product Name
THOC7 Polyclonal Antibody
Catalog Number
RD75574A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
NIF3L1 BP1 (Ngg1-interacting factor 3-like 1 binding protein 1), also known as THOC7 (THO complex subunit 7 homolog), fSAP24 or hTREX30, is a 204 amino acid cytoplasmic and nuclear protein that belongs to the THOC7 family and interacts with NIF3L1. NIF3L1 BP1 is a component of the THO/TREX complex that is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling Pol II with RNA splicing and export factors. The THO/TREX complex also plays a role in the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The gene that encodes NIF3L1 BP1 maps to human chromosome 3p14.1.
Immunogen Information
Immunogen
Recombinant protein of human THOC7
Swissprot
Q6I9Y2
Synonyms
FLJ23445fSAP24Functional spliceosome associated protein 24Functional spliceosome-associated protein 24hTREX30Ngg1 interacting factor 3 like 1 binding protein 1Ngg1 interacting factor 3 like protein 1 binding protein 1Ngg1-interacting factor 3-like
Calculated MW
24 kDa
Gene Accession
BC065012
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas