THPO Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD82354A
Western blot analysis of extracts of various cell lines using THPO Polyclonal Antibody at dilution of 1:1000.
Product Name
THPO Polyclonal Antibody
Catalog Number
RD82354A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.
Immunogen Information
Immunogen
Recombinant fusion protein of human THPO (NP_001171068.1).
Gene ID
7066
Swissprot
P40225
Synonyms
THPOMGDFMKCSFMLMPLLGTHCYT1TPO
Calculated MW
33 kDa/37 kDa
Observed MW
32 kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas