TIA1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252223A
Western blot analysis of HEPG2 and NIH/3T3 cell lysates using TIA1 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TIA1 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using TIA1 Polyclonal Antibody at dilution of 1:55(×200)
Product Name
TIA1 Polyclonal Antibody
Catalog Number
RD252223A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
P31483
Synonyms
Cytotoxic granule associated RNA binding protein 1Cytotoxic granule associated RNA binding proteinmTIA-1Nucleolysin TIA 1 isoform p40Nucleolysin TIA-1 isoform p40Nucleolysin TIA1 isoform p40p40 TIA 1p40-TIA-1 (containing p15-TIA-1)p40-TIA-1RNA b
Calculated MW
43 kDa
Observed MW
Refer to figures
Gene Accession
BC015944
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:40-1:250, ELISA 1:5000-1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.