The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Fusion protein of human TKTL1
Swissprot
P51854
Synonyms
TK 2TK2TKRTKT 2TKT2TKTL1TKTL1Transketolase 2Transketolase like 1Transketolase like protein 1Transketolase related proteintransketolase-like 1Transketolase-like protein 1Transketolase-related proteinTransketolase2
Gene Accession
BC025382
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-150, ELISA 1:2000-10000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4