The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse TLR9
Swissprot
Q9EQU3,Q9NR96
Synonyms
CD289TLR 9TLR9Toll like receptor 9Toll like receptor 9 isoform A precursorToll like receptor 9 isoform BToll-like receptor 9
Applications
Reactivity
Human,Mouse
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:100-1:500
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4