TMPRSS11F Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77208A
Western Blot analysis of Human thyroid and esophagus cancer, Human normal rectum tissue using TMPRSS11F Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human thyroid cancer using TMPRSS11F Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human gastric cancer using TMPRSS11F Polyclonal Antibody at dilution of 1:30
Product Name
TMPRSS11F Polyclonal Antibody
Catalog Number
RD77208A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.
Immunogen Information
Immunogen
Synthetic peptide of human TMPRSS11F
Swissprot
Q6ZWK6
Synonyms
Transmembrane protease serine 11FTMPRSS11FAirway trypsin-like protease 4
Calculated MW
49 kDa
Gene Accession
NP_997290
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.