TNF-α Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD90342A
Western blot analysis of extracts of HeLa cells using TNF-α  Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of HeLa cells using TNF-α Polyclonal Antibody at 1:1000 dilution.
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Overview
Circle
Product Name
TNF-α Polyclonal Antibody
Catalog Number
RD90342A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions. It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation. In mouse deficiency of this gene is associated with defects in response to bacterial infection, with defects in forming organized follicular dendritic cell networks and germinal centers, and with a lack of primary B cell follicles. Alternative splicing results in multiple transcript variants.
Immunogen Information
Circle
Immunogen
Recombinant fusion protein of mouse TNF-α
Gene ID
21926
Swissprot
P06804
Synonyms
DIFTnfaTNF-aTNFSF2Tnlg1fTnfsf1aTNFalphaTNF-alpha
Calculated MW
22kDa
Observed MW
22KDa
Applications
Circle
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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