Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
O95379
Synonyms
GG2 1Head and neck tumor and metastasis-related proteinMDC-3.13NDEDNF-kappa-B-inducible DED-containing proteinSCC S2SCC-S2SCCS2TFIP8TNF alpha-induced protein 8TNF induced proteinTNF-induced protein GG2-1TNFAIP 8TNFAIP8Tumor necrosis factor a
Gene Accession
BC007014
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-100, ELISA 1:2000-5000
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4