TNFRSF10C Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87330A
Western blot analysis of extracts of various cell lines using TNFRSF10C Polyclonal Antibody at 1:1000 dilution.
Product Name
TNFRSF10C Polyclonal Antibody
Catalog Number
RD87330A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Immunogen Information
Immunogen
Recombinant fusion protein of human TNFRSF10C
Gene ID
8794
Swissprot
O14798
Synonyms
TNFRSF10CCD263DCR1DCR1-TNFRLITTRAIL-R3TRAILR3TRID
Calculated MW
21kDa
Observed MW
25kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas