TNFRSF11B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70277A
Immunohistochemistry analysis of paraffin-embedded mouse bone using TNFRSF11B Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded Rat tooth using TNFRSF11B Polyclonal Antibody at dilution of 1:200.
Product Name
TNFRSF11B Polyclonal Antibody
Catalog Number
RD70277A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Osteoprotegerin
Swissprot
O08712,O08727
Synonyms
MGC29565OCIFOPGOsteoclastogenesis inhibitory factorOsteoprotegerinPDB5TNF receptor superfamily member 11bTNFRSF 11BTNFRSF11BTR 1TR1TR11BTumor necrosis factor receptor superfamily member 11B
Applications
Reactivity
Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200
Concentration
0.93 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas