TNFRSF11B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75300A
Western Blot analysis of Mouse kidney tissue using TNFRSF11B Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human colon cancer using TNFRSF11B Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human breast cancer using TNFRSF11B Polyclonal Antibody at dilution of 1:30
Product Name
TNFRSF11B Polyclonal Antibody
Catalog Number
RD75300A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Immunogen Information
Immunogen
Recombinant protein of human TNFRSF11B
Swissprot
O00300
Synonyms
MGC29565OCIFOPGOsteoclastogenesis inhibitory factorOsteoprotegerinPDB5TNF receptor superfamily member 11bTNFRSF 11BTNFRSF11BTR 1TR1TR11BTumor necrosis factor receptor superfamily member 11B
Calculated MW
46 kDa
Gene Accession
BC030155
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas