TNFRSF13C Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD87836A
Western blot analysis of extracts of various cell lines using TNFRSF13C Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of various cell lines using TNFRSF13C Polyclonal Antibody at 1:3000 dilution.
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Overview

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Product Name
TNFRSF13C Polyclonal Antibody
Catalog Number
RD87836A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Immunogen Information

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Immunogen
Recombinant fusion protein of human TNFRSF13C
Gene ID
115650
Swissprot
Q96RJ3
Synonyms
TNFRSF13CBAFF-RBAFFRBROMIXCD268CVID4prolixin
Calculated MW
28kDa
Observed MW
29kDa

Applications

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Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Research Areas

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