TNFRSF1B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD266102A
Immunohistochemistry of paraffin-embedded Rat kidney using TNFRSF1B Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human lung cancer using TNFRSF1B Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human rectal cancer using TNFRSF1B Polyclonal Antibody at dilution of 1:200 (40x lens).
Product Name
TNFRSF1B Polyclonal Antibody
Catalog Number
RD266102A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Immunogen Information
Immunogen
Recombinant fusion protein of human TNFRSF1B (NP_001057.1).
Gene ID
7133
Swissprot
P20333
Synonyms
CD120bTBPIITNF-R-IITNF-R75TNFBRTNFR1BTNFR2TNFR80p75p75TNFRTNF Receptor IITNFRSF1B
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.