TNFRSF8 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD84614A
Western blot analysis of extracts of various cell lines using TNFRSF8 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using TNFRSF8 Polyclonal Antibody at dilution of 1:1000.
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Overview

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Product Name
TNFRSF8 Polyclonal Antibody
Catalog Number
RD84614A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Immunogen Information

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Immunogen
A synthetic peptide of human TNFRSF8
Gene ID
943
Swissprot
P28908
Synonyms
TNFRSF8CD30D1S166EKi-1
Calculated MW
14 kDa/50 kDa/63 kDa
Observed MW
128 kDa

Applications

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Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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