The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
Immunogen Information
Immunogen
Synthetic peptide of human TNFSF13
Swissprot
O75888
Synonyms
A proliferation inducing ligandA proliferation-inducing ligandAPRILCD256TALL-2TALL2TNF related death ligandTNF- and APOL-related leukocyte expressed ligand 2TNF-related death ligand 1TNF13TNFSF13TRDL-1TRDL1Tumor necrosis factor (ligand) super
Gene Accession
NP_003799
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4