TNK2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76151A
Western Blot analysis of 231 cell using TNK2 Polyclonal Antibody at dilution of 1:1800
Immunohistochemistry of paraffin-embedded Human breast cancer using TNK2 Polyclonal Antibody at dilution of 1:70
Immunohistochemistry of paraffin-embedded Human liver cancer using TNK2 Polyclonal Antibody at dilution of 1:70
Product Name
TNK2 Polyclonal Antibody
Catalog Number
RD76151A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Immunogen Information
Immunogen
Synthetic peptide of human TNK2
Swissprot
Q07912
Synonyms
Acetate kinase 1Acetokinase 1ACK 1ACKACK-1ACK1ACK1Activated Cdc42 associated kinase 1Activated CDC42 kinase 1Activated p21cdc42Hs kinaseFLJ44758FLJ45547p21cdc42HsTNK 2TNK2Tyrosine kinase non receptor 2Tyrosine kinase non receptor protein 2
Calculated MW
119 kDa
Gene Accession
NP_005772
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas