Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
P63316
Synonyms
tnnc1aCardiac troponin Cslow skeletal and cardiac musclesTN-CTNCTnnc1TNNC1TNNI3Troponin CTroponin C slowTroponin C1 slow