TOP1MT Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western blot analysis of extracts of A-549 cells using TOP1MT Polyclonal Antibody at dilution of 1:1000.
Product Name
TOP1MT Polyclonal Antibody
Catalog Number
RD82187A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human TOP1MT (NP_443195.1).
Gene ID
116447
Swissprot
Q969P6
Synonyms
TOP1MT
Calculated MW
58 kDa/69 kDa
Observed MW
70 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:200-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas