Topors Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89117A
Western blot analysis of extracts of various cell lines using Topors Polyclonal Antibody at1:1000 dilution.
Product Name
Topors Polyclonal Antibody
Catalog Number
RD89117A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Functions as an E3 ubiquitin-protein ligase and as a E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA-damage-induced cell death through IKBKE sumoylation.
Immunogen Information
Immunogen
A synthetic peptide of mouse Topors
Gene ID
106021
Swissprot
Q80Z37
Synonyms
AW105885LUNTP53BPLp53BP3/LUNTopors
Observed MW
70kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.