TP53 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252130A
Western blot analysis of 293T cell lysate using TP53 Polyclonal Antibody at dilution of 1:1000
Product Name
TP53 Polyclonal Antibody
Catalog Number
RD252130A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
TP53,also named as P53 and NY-CO-13,belongs to the p53 family. It has 9 isoforms. In SDS-Page,the MW is about 53kd. TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. The antibody reacts specifically with 53 kDa protein.
Immunogen Information
Immunogen
Fusion protein of human TP53
Swissprot
P04637
Synonyms
Antigen NY-CO-13BCC7Cellular tumor antigen p53FLJ92943LFS1Mutant tumor protein 53p53p53 tumor suppressorP53Phosphoprotein p53Tp53Transformation related protein 53TRP53Tumor protein 53Tumor protein p53Tumor suppressor p53
Calculated MW
44 kDa
Observed MW
Refer to figures
Gene Accession
BC003596
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas