This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human TP53BP2
Swissprot
Q13625
Synonyms
53BP2Apoptosis stimulating of p53 protein 2Apoptosis stimulating protein of p53 2Apoptosis-stimulating of p53 protein 2ASPP2ASPP2BBPBcl2 binding proteinBcl2-binding proteinNY REN 51 antigenp53 binding protein 2p53-binding protein 2p53BP2PPP1R
Calculated MW
126 kDa
Gene Accession
BC040247
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4