TPX2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of K562 and A431 cells using TPX2 Polyclonal Antibody at dilution of 1/800
Product Name
TPX2 Polyclonal Antibody
Catalog Number
RD79521A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2.
Immunogen Information
Immunogen
Fusion protein of human TPX2
Swissprot
Q9ULW0
Synonyms
C20ORF1C20orf2Chromosome 20 Open Reading Frame 1Differentially expressed in cancerous and non-cancerous lung cells 2Differentially expressed in cancerous and noncancerous lung cells 2Differentially expressed in lung cells 2Differentially expressed i
Calculated MW
86 kDa
Gene Accession
BC004136
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-2000, ELISA 1:2000-5000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas