TRADD Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89140A
Western blot analysis of extracts of various cell lines using TRADD Polyclonal Antibody at 1:1000 dilution.
Product Name
TRADD Polyclonal Antibody
Catalog Number
RD89140A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Immunogen Information
Immunogen
Recombinant fusion protein of human TRADD
Gene ID
8717
Swissprot
Q15628
Synonyms
TRADDHs.89862TNFRSF1A associated via death domain
Calculated MW
17kDa
Observed MW
17kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas