TRAF4 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Immunofluorescence analysis of A549 cells using TRAF4 Polyclonal Antibody
Immunofluorescence analysis of A549 cells using TRAF4 Polyclonal Antibody
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Overview

Circle
Product Name
TRAF4 Polyclonal Antibody
Catalog Number
RD84248A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human TRAF4 (NP_004286.2).
Gene ID
9618
Swissprot
Q9BUZ4
Synonyms
TRAF4CART1MLN62RNF83

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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