The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain,a RING-type zinc finger,and two TRAF-type zinc fingers. TRAF proteins are associated with,and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized.
Immunogen Information
Immunogen
Recombinant Human TRAF5 RNF84 Protein expressed by E.coli
Swissprot
O00463
Synonyms
RING finger protein 84RNF 84RNF84TNF receptor associated factor 5TNF receptor-associated factor 5TRAF 5Traf5TRAF5
Calculated MW
57kDa
Observed MW
57kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:250-1:500,IHC 1:100-1:400
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.