The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized.
Immunogen Information
Immunogen
Recombinant Human TNF receptor-associated factor 5 protien
Swissprot
O00463
Synonyms
RING finger protein 84RNF 84RNF84TNF receptor associated factor 5TNF receptor-associated factor 5TRAF 5Traf5TRAF5
Applications
Reactivity
Human,Mouse
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:100-1:400
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.