This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Immunogen Information
Immunogen
Fusion protein of human TREM1
Swissprot
Q9NP99
Synonyms
CD354OTTMUSP00000018206TREM 1TREM-1TREM1TREM1Triggering receptor expressed on monocytes 1Triggering receptor expressed on myeloid cells 1Triggering receptor TREM 1Triggering receptor TREM1