The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region.
Immunogen Information
Immunogen
Synthetic peptide of human TRIM24
Swissprot
O15164
Synonyms
E3 ubiquitin protein ligase TRIM24E3 ubiquitin-protein ligase Trim24hTIF1PTC6RING finger protein 82RNF82TF1ATIF1TIF1-alphaTIF1ATIF1ATIF1ALPHATranscription intermediary factor 1-alphaTranscriptional intermediary factor 1 alphaTranscriptional
Calculated MW
117/113 kDa
Gene Accession
NP_056989
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4