TRIM25 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TRIM25 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TRIM25 Polyclonal Antibody at dilution 1:40
Product Name
TRIM25 Polyclonal Antibody
Catalog Number
RD77200A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Immunogen Information
Immunogen
Synthetic peptide of human TRIM25
Swissprot
Q14258
Synonyms
E3 ubiquitin/ISG15 ligase TRIM25EFPEstrogen responsive finger proteinEstrogen-responsive finger proteinRING finger protein 147RNF 147RNF147TRI25TRI25TRIM 25Trim25Tripartite motif containing 25Tripartite motif containing protein 25Tripartite m
Gene Accession
NP_005073
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.