Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).
Immunogen Information
Immunogen
Fusion protein of human TRMT12
Swissprot
Q53H54
Synonyms
Alpha amino alpha carboxypropyl transferase TYW2FLJ20772Homolog of yeast tRNA methyltransferaseRadical S-adenosyl methionine and flavodoxin domain-containing protein 2TRM 12TRM12TRMT 12TRMT12tRNA methyltransferase 12tRNA methyltransferase 12 homo