TTC12 (tetratricopeptide repeat domain 12), also known as TPARM, is a 705 amino acid cytoplasmic protein containing a TPR repeat domain and three armadillo repeat motifs. TTC12 is expressed in testis, prostate, lung, germinal center B cells, neuroblastoma, teratocarcinoma, colon cancer and gastric cancer. The gene encoding TTC12 is located in a region of human chromosome 11 that is commonly deleted in a variety of cancers, therefore, it is considered a candidate tumor suppressor gene. Human chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome.
Immunogen Information
Immunogen
Fusion protein of human TTC12
Swissprot
Q9H892
Synonyms
tetratricopeptide repeat domain 12Tetratricopeptide repeat protein 12tetratricopeptide repeat protein 12 variant 1tetratricopeptide repeat protein 12 variant 2TPARMTPR repeat protein 12TTC12TTC12