TTR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218211A
Western blot analysis of Mouse serum using TTR Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TTR Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TTR Polyclonal Antibody at dilution of 1:50(×200)
Product Name
TTR Polyclonal Antibody
Catalog Number
RD218211A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol,through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver,choroid plexus,retinal pigment epithelium,and pancreas.Within the CNS,TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis). Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR),hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1). In addition,positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. (22103483)
Immunogen Information
Immunogen
Fusion protein of human TTR
Swissprot
P02766
Synonyms
Amyloid polyneuropathyAmyloidosis IATTRCarpal tunnel syndrome 1CTSCTS1Dysprealbuminemic euthyroidal hyperthyroxinemiaDystransthyretinemic hyperthyroxinemiaEpididymis luminal protein 111HEL111HsT2651PALBPrealbumin amyloidosis type IPrealbumin
Calculated MW
16 kDa
Observed MW
Refer to figures
Gene Accession
BC005310
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
0.72 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas