The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.
Immunogen Information
Immunogen
Synthetic peptide of human TXN
Swissprot
P10599
Synonyms
ADFATL derived factorATL-derived factorDKFZp686B1993MGC61975SASPSurface associated sulphydryl proteinSurface-associated sulphydryl proteintesticular tissue protein Li 199THIOThioredoxinthioredoxin delta 3TRDXTRX 1TrxTRX1TXNTXN delta 3TXN
Calculated MW
12 kDa
Gene Accession
NP_003320
Applications
Reactivity
Human,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4