TYR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD80995A
Western blot analysis of extracts of various cell lines using TYR Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Rat heart using TYR Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of Rat skin using TYR Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of Human skin cancer using TYR Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of Mouse skin using TYR Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
TYR Polyclonal Antibody
Catalog Number
RD80995A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human TYR (NP_000363.1).
Gene ID
7299
Swissprot
P14679
Synonyms
TYRATNCMM8OCA1OCA1AOCAIASHEP3
Calculated MW
42 kDa/60 kDa
Observed MW
80 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas