The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Immunogen Information
Immunogen
Synthetic peptide of human UBA1
Swissprot
P22314
Synonyms
A1S9A1S9 proteinA1S9T and BN75 temperature sensitivity complementingA1S9TA1STAMCX1CFAP124CTD-2522E6.1GXP 1GXP1MGC4781POC20POC20 centriolar protein homologProtein A1S9SMAX2Uba1UBA1ubiquitin-activating enzyme E1 homolog AUBA1UBA1AUBE 1U
Calculated MW
118 kDa
Gene Accession
NP_695012
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4