UBA7 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252436A
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using UBA7 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using UBA7 Polyclonal Antibody at dilution of 1:35(×200)
Product Name
UBA7 Polyclonal Antibody
Catalog Number
RD252436A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
Immunogen Information
Immunogen
Fusion protein of human UBA7
Swissprot
P41226
Synonyms
D8MGC12713UBA1ubiquitin activating enzyme E1 homolog BUBA1BUBA7UBA7ubiquitin activating enzyme E1UBA7Ube 1LUBE 2UBE1LUBE2Ubiquitin activating enzyme 2Ubiquitin activating enzyme E1 homologUbiquitin Activating Enzyme E1 LikeUbiquitin activa
Gene Accession
BC006378
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas