UBP1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79124A
Western Blot analysis of PC3 cell using UBP1 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human cervical cancer using UBP1 Polyclonal Antibody at dilution of 1:40
Product Name
UBP1 Polyclonal Antibody
Catalog Number
RD79124A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
LBP1 (Upstream-binding protein 1), also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family (grainyhead transcription factor family). LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells. LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region. Null expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis.
Immunogen Information
Immunogen
Synthetic peptide of human UBP1
Swissprot
Q9NZI7
Synonyms
LBP1ALBP1BLBP-1BLBP-1a
Calculated MW
60 kDa
Gene Accession
NP_001121632
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas