The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein.
Immunogen Information
Immunogen
Synthetic peptide of human UBR4
Swissprot
Q5T4S7
Synonyms
600 kDa retinoblastoma protein associated factor600 kDa retinoblastoma protein-associated factorE3 ubiquitin-protein ligase UBR4KIAA0462KIAA1307N-recognin-4p600RBAF600Retinoblastoma associated factor 600 like proteinRetinoblastoma associated fact
Gene Accession
NP065816
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
1.1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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